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Centrifugal Filters

    Broad chemical compatibility: Heat-sealed membrane eliminates adhesives and downstream extractables; compatible with pH 1 to 9 o Reverse spin recovery: Enables maximum protein recovery without introducing pipetting errors; low binding membrane and polypropylene housing for > 90% sample recovery 

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    *Maximum initial sample volume: Swinging bucket(10.0mL), Fixed angle rotor(10.0mL)  

    *Typical final concentrate volume: 200μL 

    *Maximum relative centrifugal force: Swinging bucket rotor(4,000g), Fixed angle rotor(5,000g)

    *Active membrane area: 5.48c㎡

    *Protein Concentration, Nucleic Acid Concentraion, Buffer Exchange, Dialysis, Desalting 

    *Dead stop: Avoids spinning to dryness, provides a predictable concentration factor and no need to calibrate for several samples to run in parallel

    *Available in multiple pore sizes with the following defined Molecular Weight Cut-Offs (MWCO): 30, 50 and 100KD 

    *Vertical membranes: Aligned with filtrate rather than perpendicular for less clogging, less waste and faster filtration; capable of 25- to 80-fold concentration in a single step concentration in a single step

    *Reliable: Spin precious samples with confidence in one robust, sleek unit that prevents leakage 

    *Ultrafiltration membrane is neutrally charged, rendering it low binding for enhanced flux and recovery. The membrane has excellent chemical resistance and very low extractables 

    *Temperature range: -20°C to +50C° 

    *Autoclavability: No

    Processing of protein solutions containing biomolecules (albumin, mAbs, lgG, lgM, hormones, growth factors, etc.)

    *Acetic Acid (>25%)

    *Acetonitrile (>30%)

    *Aliphatic & aromatic esters

    *Amines

    *Ammonium hydroxide (>5%)  

    *Aromatic & chlorinated hydrocarbons

    *Butyl acetate (>40%)

    *Dimethyl acetamide (DMAC) (>30%)

    *Ethers

    *Hydrochloric acid (>0.5 Nat 50°C)

    *Isopropyl Alcohol (> 25%) 

    *Ketone

    *Methylene chloride (>1%) 

    *Methyl ethyl ketone (>1%)

    *Phosphoric acid (>1 N) 

    *Sodium deoxycholate (>5%)  

    *Sodium hydroxide (>0.5N at 50°C) 

    *Sodium hypochlorite (>0.04%)

    *Tetrahydrofuran (>5%)

    *Toluene (>1%)